SCHEMBL879722

SCHEMBL879722

Cc1cccc(C(=O)Cl)c1F

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
ALOX15 P16050 1/20 0.52
KAT6A Q92794 2/20 0.46
HPGD P15428 4/20 0.44
KDM4E B2RXH2 3/20 0.44
HSD17B10 Q99714 2/20 0.44
CES2 O00748 1/20 0.42
BCHE P06276 1/20 0.42
CES1 P23141 1/20 0.42
MYC P01106 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
KMT2A Q03164 3/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2C9 P11712 2/20 0.38
MGLL Q99685 1/20 0.37
HTT P42858 2/20 0.37
KDM4C Q9H3R0 1/20 0.37
POLB P06746 1/20 0.37
MEN1 O00255 2/20 0.36
AKR1B10 O60218 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19185970 0.84 ALDH1A1 (0.62) ALDH1A1ALOX15KAT6AHPGDCES2
SCHEMBL10644835 0.83 KAT6A (0.49) ALDH1A1KAT6AHPGDKDM4EHSD17B10
SCHEMBL10526573 0.81 KAT6A (0.47) ALDH1A1KAT6AHPGDKDM4EHSD17B10
SCHEMBL29945818 0.81 KAT6A (0.47) ALDH1A1KAT6AHPGDKDM4EHSD17B10
SCHEMBL1642296 0.81 KAT6A (0.47) ALDH1A1KAT6AHPGDKDM4EHSD17B10
SCHEMBL2396879 0.81 HPGD (0.53) ALDH1A1ALOX15KAT6AHPGDCES2
SCHEMBL698709 0.81 KDM4E (0.61) ALDH1A1ALOX15KAT6AHPGDKDM4E
SCHEMBL27834637 0.79 LMNA (0.49) ALDH1A1ALOX15HPGDKDM4EHSD17B10
SCHEMBL6459628 0.79 KAT6A (0.46) ALDH1A1KAT6AHPGDKDM4EHSD17B10
SCHEMBL15011165 0.79 KAT6A (0.54) ALDH1A1KAT6AHPGDKDM4EMYC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1616384-A Difluoroalkylaromatics BAYER CHEMICALS AG (DE) 2005-05-18 CN claimed
CN-106132923-B Oligoaniline derivative, charge-transporting varnish and organic electroluminescent device 日产化学工业株式会社 2019-11-15 CN disclosed
CN-107210377-B Varnish for forming charge-transporting thin film 日产化学工业株式会社 2019-07-05 CN disclosed
CN-109923114-A Pyrazolopyridine derivatives as HPK1 modulators and their use for the treatment of cancer 因赛特公司 2019-06-21 CN disclosed
CN-107112428-B Charge-transporting varnish and organic electroluminescent device 日产化学工业株式会社 2019-01-22 CN disclosed
CN-108698982-A FLUORINE ATOM-CONTAINING COMPOUND AND USE THEREOF 日产化学工业株式会社 2018-10-23 CN disclosed
CN-107710440-A Charge-transporting varnish and organic electroluminescent element 日产化学工业株式会社 2018-02-16 CN disclosed
CN-102977029-B As 5 HT2ASerotonin receptor modulator is applied to treat 3 phenylpyrazole derivatives of relative illness 艾尼纳制药公司 2017-12-19 CN disclosed
CN-105612146-B Aryl sulfonic acid compound and its utilization and the preparation method of aryl sulfonic acid compound 日产化学工业株式会社 2017-10-27 CN disclosed
CN-107210377-A Varnish for forming charge-transporting thin film 日产化学工业株式会社 2017-09-26 CN disclosed
WO-1997047625-A1 TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS AMERICAN CYANAMID COMPANY (US) 1997-12-18 WO disclosed
WO-1997047624-A1 TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS AMERICAN CYANAMID COMPANY (US) 1997-12-18 WO disclosed
CN-1031378-C Combating insect infestation in rice ROHM & HAAS (US) 1996-03-27 CN disclosed
CN-1030911-C Dibenzoylalkylcyanohydrazines ROHM & HAAS (US) 1996-02-07 CN disclosed
EP-0461809-B1 Dibenzoylalkylcyanohydrazines ROHM & HAAS (US) 1994-12-07 EP disclosed
CN-1019668-B process for preparing quinolone carboxylic acid derivatives KYORIN SEIYAKU KK (JP) 1992-12-30 CN disclosed
CN-1057452-A Dibenzoyl alkyl-alkyl cyanides ROHM & HAAS (US) 1992-01-01 CN disclosed
EP-0461809-A1 Dibenzoylalkylcyanohydrazines ROHM AND HAAS COMPANY (US) 1991-12-18 EP disclosed
CN-1046835-A Go out and remove the method for rice insect pest ROHM & HAAS (US) 1990-11-14 CN disclosed
CN-87101984-A Carbostyril carboxylic acid derivatives and preparation method thereof 1987-10-07 CN disclosed