Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 4/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | GLP1R | P43220 | 5/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29946162 | 0.87 | HTR6 (0.49) | HTR6SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL29946103 | 0.85 | SLC6A2 (0.39) | HTR6SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL29946087 | 0.82 | CYP19A1 (0.39) | HTR6KDM1AJAK2JAK3SLC6A2 | |
| SCHEMBL29945852 | 0.80 | GPR119 (0.53) | JAK2JAK3GPR119 | |
| SCHEMBL24497811 | 0.75 | GLP1R (0.51) | HTR6KDM1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29687402 | 0.75 | GLP1R (0.51) | HTR6KDM1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29945922 | 0.75 | SLC6A2 (0.48) | HTR6SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL24455365 | 0.74 | HTR6 (0.46) | HTR6KDM1ATLR7SLC6A2SLC6A4 | |
| SCHEMBL20280066 | 0.74 | GLP1R (0.52) | KCNH2HTR1AGLP1RCYP2C8 | |
| SCHEMBL29518203 | 0.74 | GLP1R (0.52) | KCNH2HTR1AGLP1RCYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |