Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.39 |
| ▸ | HTR1A | P08908 | 5/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29946103 | 0.89 | SLC6A2 (0.39) | HTR6SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL29945896 | 0.87 | HTR6 (0.37) | HTR6SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL29945981 | 0.86 | HTR6 (0.41) | HTR6MAPK14SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL29945922 | 0.83 | SLC6A2 (0.48) | HTR6SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL29945870 | 0.77 | SMN1; SMN2 (0.49) | — | |
| SCHEMBL29945848 | 0.73 | HTR6 (0.46) | HTR6SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL24485665 | 0.72 | HTR6 (0.54) | HTR6MAPK14SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL30149360 | 0.72 | HTR6 (0.54) | HTR6MAPK14SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL29946087 | 0.71 | CYP19A1 (0.39) | HTR6SLC6A4SLC6A2SLC6A3HTR2C | |
| SCHEMBL6926360 | 0.70 | SLC6A4 (0.51) | HTR6SLC6A4SLC6A2SLC6A3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |