Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
| ▸ | GLP1R | P43220 | 2/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29946162 | 0.89 | HTR6 (0.49) | SLC6A2SLC6A4SLC6A3HTR6HTR1A | |
| SCHEMBL29945896 | 0.85 | HTR6 (0.37) | SLC6A2SLC6A4SLC6A3HTR6HTR1A | |
| SCHEMBL29945848 | 0.81 | HTR6 (0.46) | SLC6A2SLC6A4SLC6A3HTR6NPC1 | |
| SCHEMBL29945924 | 0.78 | TRPV3 (0.44) | KMT2A | |
| SCHEMBL29945922 | 0.76 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3HTR6NPC1 | |
| SCHEMBL29945981 | 0.75 | HTR6 (0.41) | SLC6A2SLC6A4SLC6A3HTR6MCHR1 | |
| SCHEMBL24321623 | 0.75 | HTR6 (0.49) | SLC6A2SLC6A4SLC6A3HTR6NPC1 | |
| SCHEMBL20267985 | 0.73 | GLP1R (0.55) | KCNH2GLP1R | |
| SCHEMBL22402438 | 0.73 | HTR6 (0.47) | SLC6A2SLC6A4SLC6A3HTR6NPC1 | |
| SCHEMBL29394844 | 0.73 | GLP1R (0.55) | KCNH2GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |