Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29945870 | 0.91 | SMN1; SMN2 (0.49) | TRPV3MAPTDPP4SMN1; SMN2TP53 | |
| SCHEMBL29945852 | 0.87 | GPR119 (0.53) | TRPV3MAPTDPP4SMN1; SMN2 | |
| SCHEMBL29946017 | 0.85 | MEN1 (0.48) | CNR1NPSR1MEN1KMT2AUSP2 | |
| SCHEMBL29946020 | 0.85 | MEN1 (0.48) | CNR1NPSR1MEN1KMT2AUSP2 | |
| SCHEMBL29945994 | 0.81 | GPR119 (0.46) | TRPV3CNR1NPSR1CYP3A4MEN1 | |
| SCHEMBL24320996 | 0.81 | GLP1R (0.53) | TRPV3CNR1MAPTNPSR1GPR35 | |
| SCHEMBL20266522 | 0.80 | GLP1R (0.58) | — | |
| SCHEMBL22391791 | 0.80 | TRPV3 (0.47) | TRPV3CNR1MAPTNPSR1GPR35 | |
| SCHEMBL29668681 | 0.80 | GLP1R (0.58) | — | |
| SCHEMBL30209321 | 0.80 | TRPV3 (0.47) | TRPV3CNR1MAPTNPSR1GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |