SCHEMBL29946166

SCHEMBL29946166

COC(=O)CC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CC(=O)OC)C(=O)CF)[C@@H](C)O

nearest known ligand 0.72

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
REN P00797 4/20 0.51
CTSK P43235 6/20 0.50
CTSB P07858 3/20 0.49
CAPN1 P07384 1/20 0.49
CTSL P07711 3/20 0.48
CTSS P25774 2/20 0.48
PSMB1 P20618 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23133260 1.00 REN (0.51) RENCTSKCTSBCAPN1CTSL
SCHEMBL20257224 1.00 REN (0.51) RENCTSKCTSBCAPN1CTSL
SCHEMBL23133259 1.00 REN (0.51) RENCTSKCTSBCAPN1CTSL
SCHEMBL21481101 0.94 CTSK (0.56) RENCTSKCTSBCAPN1
SCHEMBL21481102 0.94 CTSK (0.56) RENCTSKCTSBCAPN1
SCHEMBL23133192 0.94 CTSK (0.56) RENCTSKCTSBCAPN1CTSL
SCHEMBL20257141 0.94 CTSK (0.56) RENCTSKCTSBCAPN1CTSL
SCHEMBL20257223 0.94 REN (0.48) RENCTSKCTSBCAPN1CTSL
SCHEMBL28714127 0.89 REN (0.52) RENCTSKCTSBCTSLCTSS
SCHEMBL29449496 0.89 REN (0.52) RENCTSKCTSBCTSLCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250146050-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2025-05-08 US disclosed
US-20250122555-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2025-04-17 US disclosed
US-12139744-B2 Stabilisation of biological samples QIAGEN GMBH (DE) 2024-11-12 US disclosed
US-12110533-B2 Stabilisation and isolation of extracellular nucleic acids QIAGEN GMBH (DE) 2024-10-08 US disclosed
US-20240287574-A1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS QIAGEN GMBH (DE) 2024-08-29 US disclosed
EP-3312273-B1 PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF UNIV TOKYO SCIENCE FOUND (JP) 2024-07-24 EP disclosed
EP-4397770-A1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS PreAnalytiX GmbH (CH) 2024-07-10 EP disclosed
EP-3401406-B1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS PREANALYTIX GMBH (CH) 2023-11-29 EP disclosed
US-11525155-B2 Stabilisation of biological samples QIAGEN GMBH (DE) 2022-12-13 US disclosed
US-20220364149-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2022-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122555-A1 STABILISATION OF BIOLOGICAL SAMPLES RNASE1, RNASEH1, EWSR1 REN 3192/4885CTSK 434/4885CTSB 300/4885
US-12139744-B2 Stabilisation of biological samples RNASE1, RNASEH1, EWSR1 REN 3192/4885CTSK 434/4885CTSB 300/4885
US-20250146050-A1 STABILISATION OF BIOLOGICAL SAMPLES RNASE1, RNASEH1, EWSR1 REN 3192/4885CTSK 434/4885CTSB 300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.