SCHEMBL29946196

SCHEMBL29946196

CC(C)(C)OC(=O)N[C@@H](CC(=O)OCc1ccccc1)C(=O)CCl

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KLK5 Q9Y337 2/20 0.58
KLK7 P49862 1/20 0.58
PPARA Q07869 3/20 0.53
CTSS P25774 4/20 0.50
CACNA1B Q00975 4/20 0.50
SYK P43405 1/20 0.50
CASP1 P29466 3/20 0.49
ACE P12821 1/20 0.49
PPARG P37231 2/20 0.48
CTSK P43235 3/20 0.48
CTSL P07711 1/20 0.48
CTSB P07858 1/20 0.48
MAPT P10636 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18103838 1.00 KLK5 (0.58) KLK5KLK7PPARACTSSCACNA1B
SCHEMBL17731584 0.91 CASP1 (0.54) KLK5KLK7PPARACTSSSYK
SCHEMBL9943562 0.88 KLK5 (0.65) KLK5KLK7PPARACTSSCACNA1B
SCHEMBL12585497 0.88 KLK5 (0.65) KLK5KLK7PPARACTSSCACNA1B
SCHEMBL84710 0.88 PPARA (0.63) KLK5KLK7PPARACTSSCACNA1B
SCHEMBL4370045 0.88 KLK5 (0.65) KLK5KLK7PPARACTSSCACNA1B
SCHEMBL344670 0.88 PPARA (0.63) KLK5KLK7PPARACTSSCACNA1B
SCHEMBL9943561 0.88 KLK5 (0.65) KLK5KLK7PPARACTSSCACNA1B
SCHEMBL344669 0.88 PPARA (0.63) KLK5KLK7PPARACTSSCACNA1B
SCHEMBL10585294 0.88 KLK5 (0.65) KLK5KLK7PPARACTSSCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250146050-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2025-05-08 US disclosed
US-20250122555-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2025-04-17 US disclosed
US-12171821-B2 Toxoplasma gondii vaccine WISCONSIN ALUMNI RESEARCH FOUNDATION (WARF) (US) 2024-12-24 US disclosed
US-12139744-B2 Stabilisation of biological samples QIAGEN GMBH (DE) 2024-11-12 US disclosed
US-12110533-B2 Stabilisation and isolation of extracellular nucleic acids QIAGEN GMBH (DE) 2024-10-08 US disclosed
EP-4397770-A1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS PreAnalytiX GmbH (CH) 2024-07-10 EP disclosed
US-20240026304-A1 Method for Producing Stem Cell Clones Suitable for Induction of Differentiation into Somatic Cells UNIV KYOTO (JP) 2024-01-25 US disclosed
EP-3401406-B1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS PREANALYTIX GMBH (CH) 2023-11-29 EP disclosed
EP-3296390-B1 METHOD FOR PRODUCING STEM CELL CLONES SUITABLE FOR INDUCTION OF DIFFERENTIATION INTO SOMATIC CELLS UNIV KYOTO (JP) 2023-01-04 EP disclosed
US-11525155-B2 Stabilisation of biological samples QIAGEN GMBH (DE) 2022-12-13 US disclosed
US-20220364149-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2022-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122555-A1 STABILISATION OF BIOLOGICAL SAMPLES RNASE1, RNASEH1, EWSR1 KLK5 1490/4885KLK7 702/4885PPARA 4333/4885
US-12139744-B2 Stabilisation of biological samples RNASE1, RNASEH1, EWSR1 KLK5 1490/4885KLK7 702/4885PPARA 4333/4885
US-20250146050-A1 STABILISATION OF BIOLOGICAL SAMPLES RNASE1, RNASEH1, EWSR1 KLK5 1490/4885KLK7 702/4885PPARA 4333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.