Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | CTSD | P07339 | 1/20 | 0.50 |
| ▸ | CDC7 | O00311 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | S100A4 | P26447 | 2/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.45 |
| ▸ | PPIA | P62937 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15741931 | 0.94 | TSHR (0.53) | KEAP1NFE2L2CTSDCDC7ALDH1A1 | |
| SCHEMBL2362517 | 0.93 | CDC7 (0.45) | KEAP1NFE2L2CTSDCDC7ALDH1A1 | |
| SCHEMBL995083 | 0.86 | LMNA (0.54) | CTSDCDC7ALDH1A1TDP1TSHR | |
| SCHEMBL29950282 | 0.86 | LMNA (0.54) | CTSDCDC7ALDH1A1TDP1TSHR | |
| SCHEMBL14120523 | 0.86 | ALDH1A1 (0.43) | KEAP1NFE2L2CTSDCDC7ALDH1A1 | |
| SCHEMBL27731050 | 0.86 | KEAP1 (0.44) | KEAP1NFE2L2CTSDCDC7ALDH1A1 | |
| SCHEMBL1083489 | 0.84 | MAPT (0.47) | KEAP1NFE2L2CTSDCDC7ALDH1A1 | |
| SCHEMBL10766788 | 0.82 | CTSD (0.65) | CTSDALDH1A1TDP1TSHRLMNA | |
| SCHEMBL115478 | 0.82 | CTSD (0.65) | CTSDALDH1A1TDP1TSHRLMNA | |
| SCHEMBL299878 | 0.82 | FBP1 (0.49) | KEAP1NFE2L2CTSDCDC7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101172958-A | N,N*-2(2substituted phenyl) derivant of - 4-methoxy-1,3-benzol diamide and use of the same | UNIV TIANJIN TECHNOLOGY (CN) | 2008-05-07 | — | — | CN | claimed |
| CN-101172958-A | N,N*-2(2substituted phenyl) derivant of - 4-methoxy-1,3-benzol diamide and use of the same | UNIV TIANJIN TECHNOLOGY (CN) | 2008-05-07 | — | — | CN | disclosed |