SCHEMBL163965

SCHEMBL163965

COC(=O)C(Cl)Cc1ccc(Cl)cc1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 2/20 0.47
PPARG P37231 2/20 0.46
PPARA Q07869 2/20 0.46
ALDH1A1 P00352 1/20 0.46
ESR1 P03372 1/20 0.46
ESR2 Q92731 1/20 0.46
FPR2 P25090 1/20 0.46
ACACB O00763 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A3 Q01959 1/20 0.44
POLB P06746 1/20 0.44
KMT2A Q03164 2/20 0.44
EPHX2 P34913 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
CNR2 P34972 1/20 0.43
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7496453 0.91 NOS2 (0.42) NOS2PPARGPPARAALDH1A1ESR1
Resorcinol SCHEMBL22551069 0.86 NLRP3 (0.45) NOS2ALDH1A1ESR1ESR2FPR2
SCHEMBL3248350 0.86 L3MBTL1 (0.49) PPARGPPARAALDH1A1ESR1ESR2
SCHEMBL4816689 0.86 ESR1 (0.63) ESR1ESR2SLC6A2KMT2A
SCHEMBL977403 0.86 ESR1 (0.46) NOS2PPARGPPARAALDH1A1ESR1
SCHEMBL5672844 0.84 LDHA (0.59) PPARGPPARAALDH1A1FPR2ACACB
SCHEMBL3204956 0.84 ATM (0.53) ALDH1A1POLBKMT2AL3MBTL1MEN1
SCHEMBL15180970 0.84 PTPRB (0.58) NOS2PPARGPPARAALDH1A1ESR1
SCHEMBL3938449 0.83 CYP4A11 (0.53) PPARAALDH1A1ESR1ESR2ACACB
SCHEMBL9570612 0.83 ESR1 (0.44) PPARGPPARAALDH1A1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 814 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230000079-A1 COMBINATION COMPRISING A TRIKETONE HERBICIDE AND A DIPHENYLETHER HERBICIDE, AND A METHOD FOR MAKING AND USING THE COMBINATION Generic Crop Science LLC (US) 2023-01-05 US claimed
EP-3954214-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS Agrivalle Brasil Industria e Comércio de Produtos Agrícolas Ltda (BR) 2022-02-16 EP claimed
US-20220015371-A1 Compositions and Methods for Reducing Pesticide-Induced Plant Damage and Improving Plant Yield PNC BANK, NATIONAL ASSOCIATION 2022-01-20 US claimed
US-20210378241-A1 COMBINATION COMPRISING A BENZAMIDE HERBICIDE AND A PYRIDINE CARBOXYLIC ACID HERBICIDE, AND A METHOD FOR MAKING AND USING THE COMBINATION Generic Crop Science LLC (US) 2021-12-09 US claimed
EP-3890491-A1 COMPOSITIONS AND METHODS FOR REDUCING PESTICIDE-INDUCED PLANT DAMAGE AND IMPROVING PLANT YIELD Cytozyme Laboratories, Inc. (US) 2021-10-13 EP claimed
US-20210120811-A1 AQUEOUS CAPSULE SUSPENSION CONCENTRATES CONTAINING A HERBICIDAL SAFENER AND A PESTICIDAL ACTIVE SUBSTANCE FMC CORPORATION 2021-04-29 US claimed
EP-3787407-A1 AQUEOUS CAPSULE SUSPENSION CONCENTRATES CONTAINING A HERBICIDAL SAFENER AND A PESTICIDAL ACTIVE SUBSTANCE Bayer Aktiengesellschaft (DE) 2021-03-10 EP claimed
WO-2020206518-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS AGRIVALLE BRASIL INDUSTRIA E COMÉRCIO DE PRODUTOS AGRÍCOLAS LTDA (BR) 2020-10-15 WO claimed
WO-2020118278-A1 COMPOSITIONS AND METHODS FOR REDUCING PESTICIDE-INDUCED PLANT DAMAGE AND IMPROVING PLANT YIELD CYTOZYME LABORATORIES, INC. (US) 2020-06-11 WO claimed
EP-2296480-B1 HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3,6-DICHLOROPYRIDINE-2-CARBOXYLIC ACID BASF SE (DE) 2018-08-08 EP claimed
EP-1087664-A1 HERBICIDAL MIXTURES HAVING A SYNERGISTIC EFFECT BASF AKTIENGESELLSCHAFT (DE) 2001-04-04 EP claimed
WO-2000062792-A2 COMPOSITIONS AND METHODS FOR CONTROLLING PESTS INSECT BIOTECHNOLOGY, INC. (US) 2000-10-26 WO claimed
WO-1999065314-A1 HERBICIDAL MIXTURES HAVING A SYNERGISTIC EFFECT BASF AKTIENGESELLSCHAFT (DE) 1999-12-23 WO claimed
EP-0613618-B1 Method for safening herbicides in crops using substituted benzopyran and tetrahydronaphthalene compounds AMERICAN CYANAMID CO (US) 1997-04-16 EP claimed
US-5407897-A Plant safening agents AMERICAN CYANAMID COMPANY (US) 1995-04-18 US claimed
EP-0613618-A1 Method for safening herbicides in crops using substituted benzopyran and tetrahydronaphthalene compounds AMERICAN CYANAMID COMPANY (US) 1994-09-07 EP claimed
EP-0113857-A1 Herbicidal agents BAYER AG (DE) 1984-07-25 EP claimed
EP-0052825-A1 Selective herbicidal agents on the basis of triazine diones BAYER AG (DE) 1982-06-02 EP claimed
EP-0005917-A1 Herbicidal method and mixtures of herbicidal heterocyclic compounds FISONS plc (GB) 1979-12-12 EP claimed
US-4021223-A BENZOFURANYL ALKYL AMINO SULFONATES BASF AKTIENGESELLSCHAFT (DT) 1977-05-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230000079-A1 COMBINATION COMPRISING A TRIKETONE HERBICIDE AND A DIPHENYLETHER HERBICIDE, AND A METHOD FOR MAKING AND USING THE COMBINATION DDT, TDO2, DNTT NOS2 1556/4885PPARG 280/4885PPARA 385/4885
US-20210378241-A1 COMBINATION COMPRISING A BENZAMIDE HERBICIDE AND A PYRIDINE CARBOXYLIC ACID HERBICIDE, AND A METHOD FOR MAKING AND USING THE COMBINATION DDT, GAP43, PDHA2 NOS2 3740/4885PPARG 26/4885PPARA 4/4885
US-20210120811-A1 AQUEOUS CAPSULE SUSPENSION CONCENTRATES CONTAINING A HERBICIDAL SAFENER AND A PESTICIDAL ACTIVE SUBSTANCE DDT, DERL1, GMDS NOS2 3422/4885PPARG 1066/4885PPARA 1568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.