Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955289 | 0.92 | CXCR2 (0.39) | ALDH1A1L3MBTL1RAB9ASMN1; SMN2HTT | |
| SCHEMBL2558310 | 0.87 | CXCR2 (0.40) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL29957784 | 0.84 | ACHE (0.43) | ALDH1A1MEN1KMT2AL3MBTL1RAB9A | |
| SCHEMBL29951232 | 0.78 | CXCR2 (0.47) | MAPTRAB9ASMN1; SMN2HTTNPC1 | |
| SCHEMBL29953808 | 0.78 | CA2 (0.43) | ALDH1A1POLBTSHRMEN1MAPT | |
| SCHEMBL2553614 | 0.77 | DHFR (0.39) | ALDH1A1MEN1MAPTKMT2AGAA | |
| SCHEMBL29956655 | 0.77 | CXCR2 (0.40) | ALDH1A1POLBTSHRMAPTKMT2A | |
| SCHEMBL29950694 | 0.75 | CXCR2 (0.40) | ALDH1A1POLBPKMMAPTKMT2A | |
| SCHEMBL15330335 | 0.73 | HSD17B10 (0.44) | ALDH1A1TSHRPKMMEN1MAPT | |
| SCHEMBL2556663 | 0.73 | MAOB (0.49) | ALDH1A1MEN1KMT2AGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |