Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 11/20 | 0.47 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955083 | 0.80 | ALOX15 (0.45) | CXCR2HTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29952150 | 0.80 | CXCR2 (0.37) | CXCR2NPC1RAB9AMAPT | |
| SCHEMBL29950832 | 0.78 | ALDH1A1 (0.39) | CXCR2CXCR1HTTNPC1RAB9A | |
| SCHEMBL29955289 | 0.76 | CXCR2 (0.39) | CXCR2CXCR1HTTNPC1RAB9A | |
| SCHEMBL29957784 | 0.75 | ACHE (0.43) | CXCR2CXCR1NPC1RAB9ACYP1A2 | |
| SCHEMBL29955730 | 0.75 | HTT (0.39) | CXCR2HTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29956655 | 0.73 | CXCR2 (0.40) | CXCR2CXCR1NPC1RAB9ACYP1A2 | |
| SCHEMBL15330335 | 0.73 | HSD17B10 (0.44) | HTTNPC1RAB9ACYP1A2CYP2C19 | |
| SCHEMBL29950694 | 0.71 | CXCR2 (0.40) | CXCR2CXCR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2558310 | 0.71 | CXCR2 (0.40) | CXCR2NPC1RAB9ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |