Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2553614 | 0.85 | DHFR (0.39) | DHFRSMN1; SMN2LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL29950832 | 0.84 | ALDH1A1 (0.39) | ACHESMN1; SMN2L3MBTL1ALDH1A1CXCR2 | |
| SCHEMBL29955289 | 0.82 | CXCR2 (0.39) | SMN1; SMN2LMNAL3MBTL1ALDH1A1CXCR2 | |
| SCHEMBL29956566 | 0.80 | DHFR (0.38) | ACHEDHFRSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL2558310 | 0.77 | CXCR2 (0.40) | SMN1; SMN2LMNAALDH1A1CXCR2MAOA | |
| SCHEMBL29956655 | 0.76 | CXCR2 (0.40) | SMN1; SMN2LMNAALDH1A1CXCR2MAOB | |
| SCHEMBL29952254 | 0.75 | DAO (0.40) | ACHESMN1; SMN2L3MBTL1MAOAMAOB | |
| SCHEMBL29951232 | 0.75 | CXCR2 (0.47) | SMN1; SMN2LMNACXCR2NPC1RAB9A | |
| SCHEMBL29950694 | 0.74 | CXCR2 (0.40) | SMN1; SMN2ALDH1A1CXCR2MAOBNPC1 | |
| SCHEMBL19997230 | 0.74 | ACHE (0.57) | ACHEDHFRP2RX7ALDH1A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |