Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10941882 | 0.82 | MEN1 (0.55) | GAACYP1A2CYP2D6CYP2C9MAPK1 | |
| SCHEMBL29954956 | 0.82 | MEN1 (0.55) | GAACYP1A2CYP2D6CYP2C9MAPK1 | |
| SCHEMBL2062443 | 0.79 | KEAP1 (0.51) | GAATDP1HTR7HTR6KDM4E | |
| SCHEMBL4515445 | 0.79 | PARP1 (0.44) | TDP1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29950892 | 0.79 | CCNB2 (0.53) | GAATDP1BCHEACHEMEN1 | |
| SCHEMBL2062055 | 0.79 | LMNA (0.57) | GAACYP1A2CYP2D6HTR7HTR3A | |
| SCHEMBL3198006 | 0.79 | LMNA (0.51) | CYP1A2CYP2C9MAPK1CYP2C19HTR7 | |
| SCHEMBL14252828 | 0.78 | MAPT (0.40) | GAAHTR6BLMKDM4EALDH1A1 | |
| SCHEMBL31429037 | 0.77 | ALDH1A1 (0.58) | CYP1A2HTR1DCYP2C19HTR7HTR6 | |
| SCHEMBL29950544 | 0.77 | SMN1; SMN2 (0.44) | GAAHTR1DHSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |