Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.44 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.44 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1043542 | 0.82 | PTPN1 (0.38) | ENPP2ORAI1ORAI2ORAI3MAOB | |
| SCHEMBL3783762 | 0.80 | MGLL (0.43) | ORAI1ORAI2ORAI3LMNAKDM4E | |
| SCHEMBL203282 | 0.80 | ENPP2 (0.60) | ENPP2ORAI1ORAI2ORAI3HPGD | |
| SCHEMBL7227159 | 0.79 | ENPP2 (0.46) | ENPP2ORAI1ORAI2ORAI3HPGD | |
| SCHEMBL25153580 | 0.77 | ENPP2 (0.36) | ENPP2ORAI1ORAI2ORAI3MAOB | |
| SCHEMBL1396708 | 0.77 | MGLL (0.38) | ENPP2ORAI1ORAI2ORAI3LMNA | |
| SCHEMBL519872 | 0.76 | ENPP2 (0.50) | ENPP2ORAI1ORAI2ORAI3HPGD | |
| SCHEMBL29956479 | 0.76 | GABRA1 (0.39) | ARATMKDM4EALDH1A1ALOX12 | |
| SCHEMBL22462781 | 0.76 | AR (0.43) | MAOBARATMHPGDLMNA | |
| SCHEMBL24425048 | 0.76 | CA2 (0.45) | LMNAALDH1A1ALOX12CA2PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |