Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10941882 | 1.00 | MEN1 (0.55) | MEN1KMT2ANPC1RAB9AUSP2 | |
| SCHEMBL29955688 | 0.85 | MITF (0.51) | MEN1KMT2ANPC1RAB9AUSP2 | |
| SCHEMBL29363427 | 0.82 | KDM4E (0.46) | MEN1KMT2ANPC1RAB9AUSP2 | |
| SCHEMBL3198006 | 0.82 | LMNA (0.51) | MEN1KMT2ANPC1RAB9AUSP2 | |
| SCHEMBL29951087 | 0.82 | GAA (0.54) | MEN1KMT2ANPC1RAB9AUSP2 | |
| SCHEMBL24522294 | 0.82 | KDM4E (0.46) | MEN1KMT2ANPC1RAB9AUSP2 | |
| SCHEMBL2062055 | 0.82 | LMNA (0.57) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4515445 | 0.82 | PARP1 (0.44) | MEN1KMT2ANPC1RAB9AUSP2 | |
| SCHEMBL2062443 | 0.82 | KEAP1 (0.51) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL15331998 | 0.80 | ALDH1A1 (0.50) | MEN1KMT2ANPC1RAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |