Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 3/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2521376 | 0.78 | TTR (0.48) | TTRHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL29465748 | 0.76 | HTR3E (0.47) | NOTUMMGLLTTRHTR3EHTR3B | |
| SCHEMBL177582 | 0.76 | HTR3E (0.47) | NOTUMMGLLTTRHTR3EHTR3B | |
| SCHEMBL177526 | 0.76 | TTR (0.50) | NOTUMMGLLTTRHTR3EHTR3B | |
| SCHEMBL23216410 | 0.72 | TTR (0.41) | TTRKDRENPP2HPGDHSD17B10 | |
| SCHEMBL27796545 | 0.72 | ALDH1A1 (0.52) | NOTUMHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL16654312 | 0.70 | HPGD (0.52) | TTRKDRENPP2HPGDHSD17B10 | |
| SCHEMBL6222180 | 0.70 | NOTUM (0.43) | NOTUMHPGDCYP3A4TSHR | |
| SCHEMBL29636128 | 0.69 | MGLL (0.39) | MGLL | |
| SCHEMBL24425075 | 0.69 | MGLL (0.39) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |