Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 7/20 | 0.43 |
| ▸ | CDK8 | P49336 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | LYN | P07948 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | FER | P16591 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | MARK3 | P27448 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28523488 | 0.76 | AXL (0.44) | AXLCDK8KDM4EGSK3BTNIK | |
| SCHEMBL18363126 | 0.76 | CDK8 (0.44) | AXLCDK8KDM4EGSK3BTNIK | |
| SCHEMBL29958035 | 0.72 | JAK2 (0.44) | AXLCDK8TNIKPLK4PRKD3 | |
| SCHEMBL29951554 | 0.71 | MAP4K1 (0.39) | KDM4EPIM1PIM3CLK4MKNK2 | |
| SCHEMBL29953859 | 0.70 | PSMD14 (0.44) | KDM4EGSK3BPRKD3KDRFLT3 | |
| SCHEMBL29954554 | 0.69 | ALDH1A1 (0.51) | AXLCDK8KDM4EGSK3BTNIK | |
| SCHEMBL29954564 | 0.67 | MAPT (0.61) | AXLKDM4EAURKB | |
| SCHEMBL24659982 | 0.64 | KDM4E (0.49) | AXLCDK8KDM4EGSK3BTNIK | |
| SCHEMBL23098900 | 0.64 | MGLL (0.50) | KDM4E | |
| SCHEMBL31665907 | 0.64 | PIK3CD (0.54) | AXLCDK8KDM4EGSK3BTNIK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |