Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | CTSK | P43235 | 4/20 | 0.36 |
| ▸ | CTSB | P07858 | 3/20 | 0.36 |
| ▸ | CTSS | P25774 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2552397 | 0.87 | MAPT (0.49) | HPGDALDH1A1L3MBTL1KDM4ETDP1 | |
| SCHEMBL2562763 | 0.86 | HPGD (0.41) | HPGDALDH1A1L3MBTL1KDM4ETDP1 | |
| SCHEMBL27711029 | 0.85 | HPGD (0.43) | HPGDALDH1A1L3MBTL1KDM4ETDP1 | |
| SCHEMBL29951726 | 0.83 | HTT (0.39) | ALDH1A1CTSKCTSBCTSSKDM4E | |
| SCHEMBL15330401 | 0.82 | ALDH1A1 (0.45) | HPGDALDH1A1L3MBTL1KDM4ETDP1 | |
| SCHEMBL2558206 | 0.81 | L3MBTL1 (0.41) | HPGDALDH1A1L3MBTL1KDM4ESIGMAR1 | |
| SCHEMBL2560224 | 0.81 | ALDH1A1 (0.47) | HPGDALDH1A1L3MBTL1KDM4ETDP1 | |
| SCHEMBL2555957 | 0.81 | HPGD (0.41) | HPGDALDH1A1L3MBTL1KDM4ETDP1 | |
| SCHEMBL29957137 | 0.81 | KDM4E (0.42) | HPGDALDH1A1L3MBTL1KDM4ETDP1 | |
| SCHEMBL29952645 | 0.80 | SIGMAR1 (0.43) | HPGDALDH1A1KDM4ETDP1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |