Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TDP2 | O95551 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PLG | P00747 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | PLAT | P00750 | 1/20 | 0.49 |
| ▸ | KLK1 | P06870 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9098394 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KDM4ETDP1POLBKMT2A | |
| SCHEMBL5751216 | 0.86 | ALDH1A1 (0.41) | ALDH1A1KDM4ETDP1POLBKMT2A | |
| SCHEMBL5746401 | 0.86 | ALDH1A1 (0.41) | ALDH1A1KDM4ETDP1POLBKMT2A | |
| SCHEMBL29951355 | 0.85 | ALDH1A1 (0.48) | ALDH1A1KDM4ETDP1POLBKMT2A | |
| SCHEMBL9883875 | 0.78 | KIF11 (0.42) | ALDH1A1KDM4ETDP1POLBKMT2A | |
| SCHEMBL5617799 | 0.78 | ALDH1A1 (0.56) | ALDH1A1KDM4ETDP1POLBKMT2A | |
| SCHEMBL476028 | 0.77 | CTDSP1 (0.53) | ALDH1A1KDM4ETDP1PLAUHPGD | |
| SCHEMBL29957506 | 0.77 | CTDSP1 (0.53) | ALDH1A1KDM4ETDP1PLAUHPGD | |
| SCHEMBL4102305 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KDM4ETDP1POLBKMT2A | |
| SCHEMBL5381553 | 0.77 | PTGER4 (0.50) | ALDH1A1KDM4EPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |