Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5406345 | 0.85 | ALDH1A1 (0.50) | ALDH1A1CYP2A6CYP1A2KIF11MEN1 | |
| SCHEMBL215676 | 0.81 | CYP2A6 (0.48) | ALDH1A1CYP2A6CYP1A2MEN1KMT2A | |
| SCHEMBL9883875 | 0.78 | KIF11 (0.42) | ALDH1A1CYP2A6KIF11MEN1KMT2A | |
| SCHEMBL5617799 | 0.78 | ALDH1A1 (0.56) | ALDH1A1CYP2A6CYP1A2KIF11MEN1 | |
| SCHEMBL5381553 | 0.77 | PTGER4 (0.50) | ALDH1A1CYP2A6KIF11MEN1KMT2A | |
| SCHEMBL476028 | 0.77 | CTDSP1 (0.53) | ALDH1A1CYP2A6CYP1A2KIF11TDP1 | |
| SCHEMBL29953436 | 0.77 | PTGER4 (0.50) | ALDH1A1CYP2A6KIF11MEN1KMT2A | |
| SCHEMBL3257311 | 0.77 | CYP2A6 (0.57) | ALDH1A1CYP2A6CYP1A2KIF11KMT2A | |
| SCHEMBL29951748 | 0.77 | ALDH1A1 (0.50) | ALDH1A1CYP2A6CYP1A2KIF11MEN1 | |
| SCHEMBL29957704 | 0.77 | CYP2A6 (0.57) | ALDH1A1CYP2A6CYP1A2KIF11KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103539737-B | A kind of azepine phenanthro- fluorene kind derivative, preparation method and electroluminescent fluorescent luminescent device | TCL集团股份有限公司 | 2017-03-08 | — | — | CN | disclosed |
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | PROSIDION LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | PROSIDION LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | PROSIDION LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| CN-101155817-A | Dihydroimidazothiazole derivatives | PROSIDION LTD (GB) | 2008-04-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | TPH1, HTR3B, HTR1A | ALDH1A1 195/4885CYP2A6 447/4885CYP1A2 137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.