Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954575 | 0.83 | CHRM2 (0.47) | ALDH1A1MEN1KMT2ACHRM2APP | |
| SCHEMBL29952335 | 0.80 | SLC6A2 (0.41) | ALDH1A1KDM4ELTA4HL3MBTL1MEN1 | |
| SCHEMBL29951479 | 0.78 | ENPP2 (0.49) | L3MBTL1ACHE | |
| SCHEMBL29954989 | 0.77 | LPL (0.42) | L3MBTL1MEN1KMT2AACHE | |
| SCHEMBL29957562 | 0.77 | L3MBTL1 (0.41) | LTA4HL3MBTL1ACKR3ACHE | |
| SCHEMBL30643134 | 0.77 | KDM4E (0.44) | ALDH1A1KDM4EL3MBTL1PYCR1MEN1 | |
| SCHEMBL29954644 | 0.76 | SLC6A2 (0.44) | SLC6A2SLC6A4 | |
| SCHEMBL7020409 | 0.74 | ENPP2 (0.38) | ALDH1A1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL29953487 | 0.73 | CHRM2 (0.48) | L3MBTL1CHRM2APPACHE | |
| SCHEMBL2557697 | 0.70 | FDPS (0.47) | ALDH1A1KDM4ELTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |