Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953487 | 0.80 | CHRM2 (0.48) | CHRM2L3MBTL1APPBCHECHRM1 | |
| SCHEMBL29951863 | 0.80 | ALDH1A1 (0.40) | SLC6A2SLC6A4ALDH1A1KDM4EMEN1 | |
| SCHEMBL29957562 | 0.78 | L3MBTL1 (0.41) | L3MBTL1LTA4HBCHEACHEACKR3 | |
| SCHEMBL29957787 | 0.75 | SLC6A4 (0.51) | SLC6A2SLC6A4 | |
| SCHEMBL29951258 | 0.73 | OPRM1 (0.46) | ALDH1A1KDM4EMEN1KMT2ABCHE | |
| SCHEMBL29954575 | 0.73 | CHRM2 (0.47) | ALDH1A1MEN1KMT2ACHRM2APP | |
| SCHEMBL30396772 | 0.73 | IDO1 (0.39) | ALDH1A1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL28983761 | 0.73 | IDO1 (0.39) | ALDH1A1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL29954989 | 0.70 | LPL (0.42) | MEN1KMT2AL3MBTL1BCHEACHE | |
| SCHEMBL902030 | 0.67 | IDO1 (0.34) | SLC6A2SLC6A4KDM4EACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |