SCHEMBL29951897

SCHEMBL29951897

CCC(C)Nc1ncc(C=O)cn1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACACB O00763 7/20 0.43
HCAR3 P49019 2/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
ALDH1A1 P00352 3/20 0.41
TP53 P04637 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CYP3A4 P08684 2/20 0.41
HSP90AA1 P07900 1/20 0.41
THRB P10828 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
CASP1 P29466 1/20 0.41
HIF1A Q16665 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP1A2 P05177 2/20 0.39
CYP2C19 P33261 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
DHODH Q02127 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29958037 0.82 CDK4 (0.40) ACACBHCAR3L3MBTL1ALDH1A1TDP1
SCHEMBL24567546 0.77 MEN1 (0.45) ACACBHCAR3L3MBTL1ALDH1A1TP53
SCHEMBL15022600 0.77 RAB9A (0.45) ACACBHCAR3L3MBTL1ALDH1A1TP53
SCHEMBL23852654 0.75 TAS1R3 (0.37) ACACBHCAR3ALDH1A1SMN1; SMN2
SCHEMBL9272660 0.74 ALDH1A1 (0.48) ACACBHCAR3L3MBTL1ALDH1A1TP53
SCHEMBL3719041 0.74 HCAR3 (0.53) ACACBHCAR3CYP1A2CYP2C19MEN1
SCHEMBL26085322 0.72 DHODH (0.37) ACACBHCAR3DHODH
SCHEMBL29958007 0.72 ALDH1A1 (0.41) ACACBHCAR3L3MBTL1ALDH1A1TP53
SCHEMBL29954362 0.72 ESR1 (0.44) ACACBHCAR3ALDH1A1
SCHEMBL7040045 0.72 ALDH1A1 (0.69) HCAR3L3MBTL1ALDH1A1TP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed