Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.48 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 7/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2563476 | 0.87 | USP30 (0.43) | USP30CTSAACACBDRD2HTR1A | |
| SCHEMBL29954544 | 0.87 | USP30 (0.50) | USP30ACACBPARP1TP53BP1 | |
| SCHEMBL2563048 | 0.81 | USP30 (0.39) | USP30TP53BP1 | |
| SCHEMBL29953644 | 0.80 | USP30 (0.45) | USP30ACACBPARP1CHIADRD2 | |
| SCHEMBL15330360 | 0.74 | USP30 (0.45) | USP30ACACBTP53BP1 | |
| SCHEMBL27544889 | 0.72 | CYP17A1 (0.41) | — | |
| SCHEMBL29132185 | 0.72 | HRH4 (0.35) | — | |
| SCHEMBL30790721 | 0.71 | CYP17A1 (0.44) | ACACB | |
| SCHEMBL18135099 | 0.68 | NFKB1 (0.51) | USP30CTSAPARP1TP53BP1 | |
| SCHEMBL162424 | 0.68 | PARP1 (0.45) | PARP1SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |