Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 6/20 | 0.39 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330360 | 0.88 | USP30 (0.45) | USP30ACACBTP53BP1HRH4 | |
| SCHEMBL29951919 | 0.87 | USP30 (0.48) | USP30ACACBTP53BP1PARP1 | |
| SCHEMBL2562359 | 0.83 | USP30 (0.41) | USP30TP53BP1HRH4 | |
| SCHEMBL29953644 | 0.78 | USP30 (0.45) | USP30ACACBPARP1NUDT1 | |
| SCHEMBL2563476 | 0.74 | USP30 (0.43) | USP30ACACBTP53BP1HRH4 | |
| SCHEMBL4687065 | 0.71 | CHKA (0.52) | KDM4E | |
| SCHEMBL2563048 | 0.68 | USP30 (0.39) | USP30TP53BP1 | |
| SCHEMBL18135099 | 0.68 | NFKB1 (0.51) | USP30TP53BP1PARP1HRH4 | |
| SCHEMBL10225678 | 0.68 | KDM4E (0.41) | KDM4E | |
| SCHEMBL10224847 | 0.67 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |