Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
| ▸ | USP14 | P54578 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7819729 | 0.85 | ENPP2 (0.36) | BACE1ENPP2CA1CA2 | |
| SCHEMBL9030829 | 0.79 | LPL (0.46) | BACE1ENPP2CA1CA2LPL | |
| SCHEMBL3866189 | 0.79 | DUT (0.35) | ENPP2CA1CA2LPLLIPG | |
| SCHEMBL1241080 | 0.77 | ENPP2 (0.49) | ENPP2LPLLIPG | |
| SCHEMBL20320313 | 0.76 | BACE1 (0.33) | BACE1ENPP2CA1CA2 | |
| SCHEMBL4513196 | 0.76 | GAA (0.37) | BACE1 | |
| SCHEMBL6155969 | 0.76 | IDO1 (0.38) | BACE1 | |
| SCHEMBL22233890 | 0.75 | ENPP2 (0.33) | ENPP2CA1CA2 | |
| SCHEMBL23199584 | 0.74 | KDM4E (0.35) | BACE1 | |
| SCHEMBL20742245 | 0.74 | BACE1 (0.45) | BACE1ENPP2LIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |