Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20346192 | 0.79 | BACE1 (0.32) | BACE1TACR1 | |
| SCHEMBL20346233 | 0.78 | BACE1 (0.35) | BACE1TACR1 | |
| SCHEMBL29952079 | 0.76 | BACE1 (0.36) | BACE1CA1CA2ENPP2 | |
| SCHEMBL1241080 | 0.74 | ENPP2 (0.49) | ENPP2 | |
| SCHEMBL9030829 | 0.73 | LPL (0.46) | BACE1CA1CA2ENPP2 | |
| SCHEMBL20313010 | 0.73 | LPL (0.44) | CA1CA2ENPP2 | |
| SCHEMBL14488240 | 0.73 | — | — | |
| SCHEMBL7819729 | 0.71 | ENPP2 (0.36) | BACE1CA1CA2ENPP2 | |
| SCHEMBL20346379 | 0.70 | MAPT (0.37) | — | |
| SCHEMBL20346198 | 0.70 | PGR (0.33) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210101915-A1 | NEAR-IR GLUCOSE SENSORS | PROFUSA, INC. (US) | 2021-04-08 | — | — | US | disclosed |
| US-10717751-B2 | Near-IR glucose sensors | PROFUSA, INC. (US) | 2020-07-21 | — | — | US | disclosed |
| WO-2018125913-A1 | NEAR-IR GLUCOSE SENSORS | PROFUSA, INC. (US) | 2018-07-05 | — | — | WO | disclosed |
| US-20180179233-A1 | NEAR-IR GLUCOSE SENSORS | PROFUSA, INC. (US) | 2018-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210101915-A1 | NEAR-IR GLUCOSE SENSORS | IRS1, INSR, SLC2A4 | BACE1 4307/4885CA1 2222/4885CA2 935/4885 |
| US-20180179233-A1 | NEAR-IR GLUCOSE SENSORS | IRS1, INSR, SLC2A4 | BACE1 4307/4885CA1 2222/4885CA2 935/4885 |
| US-10717751-B2 | Near-IR glucose sensors | IRS1, G6PD, SLC2A8 | BACE1 1245/4885CA1 180/4885CA2 433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.