SCHEMBL6536289

SCHEMBL6536289

COc1cc(C=O)ccc1OCC(=O)O

nearest known ligand 0.74

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.74
ALDH1A1 P00352 7/20 0.72
SMN1; SMN2 Q16637 2/20 0.72
FDPS P14324 1/20 0.69
KDM4E B2RXH2 1/20 0.65
HDAC1 Q13547 1/20 0.65
HDAC2 Q92769 1/20 0.65
HDAC8 Q9BY41 1/20 0.65
TSHR P16473 1/20 0.64
APP P05067 2/20 0.62
NPC1 O15118 1/20 0.60
CYP2C9 P11712 1/20 0.60
RAB9A P51151 1/20 0.60
NPSR1 Q6W5P4 1/20 0.60
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5246469 0.94 POLB (0.65) POLBALDH1A1SMN1; SMN2FDPSKDM4E
SCHEMBL29956334 0.94 POLB (0.65) POLBALDH1A1SMN1; SMN2FDPSKDM4E
SCHEMBL14787928 0.90 ALDH1A1 (0.63) POLBALDH1A1SMN1; SMN2FDPSKDM4E
SCHEMBL18095848 0.88 ALDH1A1 (0.72) POLBALDH1A1SMN1; SMN2FDPSKDM4E
SCHEMBL2284391 0.86 ALDH1A1 (0.74) POLBALDH1A1SMN1; SMN2FDPSKDM4E
SCHEMBL7390751 0.86 ALDH1A1 (0.76) POLBALDH1A1SMN1; SMN2FDPSKDM4E
SCHEMBL2556186 0.86 ALDH1A1 (0.76) POLBALDH1A1SMN1; SMN2FDPSKDM4E
SCHEMBL25747640 0.85 POLB (0.75) POLBALDH1A1SMN1; SMN2FDPSKDM4E
SCHEMBL7466603 0.85 FDPS (0.74) POLBALDH1A1SMN1; SMN2FDPSKDM4E
SCHEMBL16294326 0.85 ALDH1A1 (0.55) POLBALDH1A1SMN1; SMN2FDPSKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12369577-B2 Monoterpenoid/phenylpropanoid-containing compounds and methods of their making and use as baits KITTRICH CORPORATION (US) 2025-07-29 US disclosed
US-20250091994-A1 RAS/RAF BINDING INHIBITOR COMPOUND NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2025-03-20 US disclosed
US-12213479-B2 Monoterpenoid/phenylpropanoid-containing compounds and methods of their making and use as herbicides KITTRICH CORPORATION (US) 2025-02-04 US disclosed
CN-114988997-B Method for preparing ethyl vanillin crystals by adopting carboxymethyl chitosan gel 重庆科技学院 2023-06-30 CN disclosed
US-20230200386-A1 MONOTERPENOID/PHENYLPROPANOID-CONTAINING COMPOUNDS AND METHODS OF THEIR MAKING AND USE AS HERBICIDES IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2023-06-29 US disclosed
US-20230200386-A1 MONOTERPENOID/PHENYLPROPANOID-CONTAINING COMPOUNDS AND METHODS OF THEIR MAKING AND USE AS HERBICIDES IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2023-06-29 US disclosed
US-20230189802-A1 MONOTERPENOID/PHENYLPROPANOID-CONTAINING COMPOUNDS AND METHODS OF THEIR MAKING AND USE AS BAITS KITTRICH CORPORATION 2023-06-22 US disclosed
US-20230189802-A1 MONOTERPENOID/PHENYLPROPANOID-CONTAINING COMPOUNDS AND METHODS OF THEIR MAKING AND USE AS BAITS KITTRICH CORPORATION 2023-06-22 US disclosed
WO-2023008577-A1 RAS/RAF BINDING INHIBITOR COMPOUND 国立大学法人神戸大学 2023-02-02 WO disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
EP-0547104-A1 THIAZOLIDIN DERIVATIVES CEDONA PHARMACEUTICALS B.V. (NL) 1993-06-23 EP disclosed
EP-0541634-A1 1,4-DIHYDROPYRIDINE DERIVATIVES CEDONA PHARMACEUTICALS B.V. (NL) 1993-05-19 EP disclosed
EP-0240256-B1 COMPOUNDS USEFUL IN TREATING SICKLE CELL ANEMIA MERCK & CO. INC. (US) 1992-04-29 EP disclosed
WO-1992004337-A1 THIAZOLIDIN DERIVATIVES CEDONA PHARMACEUTICALS BV (NL) 1992-03-19 WO disclosed
WO-1992002503-A1 NOVEL 1,4-DIHYDROPYRIDINE DERIVATIVES CEDONA PHARMACEUTICALS BV (NL) 1992-02-20 WO disclosed
US-4751244-A NITROALKENYL CARBOXYLIC ACIDS MERCK & CO., INC. (US) 1988-06-14 US disclosed
EP-0240256-A2 Compounds useful in treating sickle cell anemia MERCK & CO. INC. (US) 1987-10-07 EP disclosed
EP-0103197-B1 ACIDIC O-NITROAROMATICS AS PHOTOINHIBITORS OF POLYMERIZATION IN POSITIVE WORKING FILMS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-01-22 EP disclosed
US-4477556-A Acidic o-nitroaromatics as photoinhibitors of polymerization in positive working films E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-16 US disclosed
EP-0103197-A1 Acidic O-nitroaromatics as photoinhibitors of polymerization in positive working films E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-03-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12369577-B2 Monoterpenoid/phenylpropanoid-containing compounds and methods of their making and use as baits CYP51A1, CYP4A22, ACHE POLB 4751/4885ALDH1A1 1885/4885SMN1; SMN2 2528/4885
US-20250091994-A1 RAS/RAF BINDING INHIBITOR COMPOUND BRAF, RAF1, NRAS POLB 3285/4885ALDH1A1 2352/4885SMN1; SMN2 4832/4885
US-20230189802-A1 MONOTERPENOID/PHENYLPROPANOID-CONTAINING COMPOUNDS AND METHODS OF THEIR MAKING AND USE AS BAITS CYP51A1, CYP4A22, ACHE POLB 4751/4885ALDH1A1 1885/4885SMN1; SMN2 2528/4885
US-20230200386-A1 MONOTERPENOID/PHENYLPROPANOID-CONTAINING COMPOUNDS AND METHODS OF THEIR MAKING AND USE AS HERBICIDES DDT, CYP4B1, GSTO1 POLB 4046/4885ALDH1A1 161/4885SMN1; SMN2 3236/4885
US-12213479-B2 Monoterpenoid/phenylpropanoid-containing compounds and methods of their making and use as herbicides DDT, CYP4B1, GSTO1 POLB 4046/4885ALDH1A1 161/4885SMN1; SMN2 3236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.