Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK1 | Q13153 | 17/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.44 |
| ▸ | PAK2 | Q13177 | 6/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6524530 | 0.83 | MAPT (0.43) | PAK1KCNH2PAK2PKM | |
| SCHEMBL25226484 | 0.82 | PAK1 (0.44) | PAK1KCNH2PAK2PKM | |
| SCHEMBL1028959 | 0.82 | RXFP1 (0.46) | PAK1KCNH2PAK2PKM | |
| SCHEMBL26074253 | 0.79 | PAK1 (0.43) | PAK1KCNH2PAK2PKM | |
| SCHEMBL25420703 | 0.77 | JAK2 (0.42) | PAK1KCNH2PAK2 | |
| SCHEMBL3834300 | 0.77 | ALDH1A1 (0.40) | PAK1KCNH2PAK2 | |
| SCHEMBL6525242 | 0.76 | ATAD2 (0.40) | PAK1KCNH2PAK2PKM | |
| SCHEMBL13907450 | 0.73 | MAPT (0.49) | PAK1KCNH2PAK2PKM | |
| SCHEMBL9292198 | 0.72 | HSP90AA1 (0.49) | — | |
| SCHEMBL6524527 | 0.72 | CASP1 (0.40) | PAK1KCNH2PAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184767-A1 | SUBSTITUTED OXAZOLIDINONES AND USE THEREOF | ROHRIG SUSANNE | 2010-07-22 | — | — | US | disclosed |
| US-20100184767-A1 | SUBSTITUTED OXAZOLIDINONES AND USE THEREOF | ROHRIG SUSANNE | 2010-07-22 | — | — | US | disclosed |
| US-20100184767-A1 | SUBSTITUTED OXAZOLIDINONES AND USE THEREOF | ROHRIG SUSANNE | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184767-A1 | SUBSTITUTED OXAZOLIDINONES AND USE THEREOF | XDH, OXA1L, PPOX | PAK1 3523/4885KCNH2 2874/4885PAK2 3303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.