Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955447 | 0.82 | KMT2A (0.46) | KMT2AALDH1A1MEN1TDP1CYP1A2 | |
| SCHEMBL2559520 | 0.82 | RORC (0.41) | KMT2AALDH1A1MEN1TDP1RORC | |
| SCHEMBL29951041 | 0.81 | KMT2A (0.48) | KMT2AALDH1A1MEN1TDP1CYP1A2 | |
| SCHEMBL15332332 | 0.77 | POLB (0.36) | KMT2AALDH1A1MEN1TDP1RORC | |
| SCHEMBL29957441 | 0.75 | ALDH1A1 (0.39) | KMT2AALDH1A1MEN1TDP1CYP1A2 | |
| SCHEMBL29951670 | 0.74 | MEN1 (0.40) | KMT2AALDH1A1MEN1TDP1LMNA | |
| SCHEMBL29952523 | 0.71 | ALDH1A1 (0.44) | KMT2AALDH1A1MEN1TDP1CYP1A2 | |
| SCHEMBL29951982 | 0.70 | ALDH1A1 (0.43) | KMT2AALDH1A1MEN1TDP1CYP1A2 | |
| SCHEMBL2560571 | 0.69 | ALDH1A1 (0.37) | ALDH1A1TSHR | |
| SCHEMBL2556059 | 0.69 | ERN1 (0.35) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |