Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2559520 | 0.88 | RORC (0.41) | KMT2AMEN1ALDH1A1TDP1LMNA | |
| SCHEMBL29957441 | 0.87 | ALDH1A1 (0.39) | KMT2AMEN1ALDH1A1TDP1LMNA | |
| SCHEMBL29955447 | 0.85 | KMT2A (0.46) | KMT2AMEN1ALDH1A1TDP1LMNA | |
| SCHEMBL29952257 | 0.81 | KMT2A (0.42) | KMT2AMEN1ALDH1A1TDP1LMNA | |
| SCHEMBL29951670 | 0.79 | MEN1 (0.40) | KMT2AMEN1ALDH1A1TDP1LMNA | |
| SCHEMBL29954704 | 0.76 | KMT2A (0.42) | KMT2AMEN1ALDH1A1TDP1LMNA | |
| SCHEMBL29951806 | 0.75 | KMT2A (0.41) | KMT2AMEN1ALDH1A1TDP1LMNA | |
| SCHEMBL29952279 | 0.74 | ALDH3A1 (0.41) | KMT2AMEN1ALDH1A1TDP1LMNA | |
| SCHEMBL29955172 | 0.73 | TDP1 (0.41) | KMT2AMEN1ALDH1A1TDP1LMNA | |
| SCHEMBL29955618 | 0.71 | KMT2A (0.43) | KMT2AMEN1ALDH1A1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |