Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951041 | 0.87 | KMT2A (0.48) | ALDH1A1KMT2AMEN1TDP1LMNA | |
| SCHEMBL2559520 | 0.81 | RORC (0.41) | ALDH1A1KMT2AMEN1TDP1LMNA | |
| SCHEMBL29954875 | 0.79 | ALDH1A1 (0.34) | ALDH1A1KMT2AMEN1TDP1LMNA | |
| SCHEMBL29955447 | 0.79 | KMT2A (0.46) | ALDH1A1KMT2AMEN1TDP1LMNA | |
| SCHEMBL29952279 | 0.79 | ALDH3A1 (0.41) | ALDH1A1KMT2AMEN1TDP1LMNA | |
| SCHEMBL29952257 | 0.75 | KMT2A (0.42) | ALDH1A1KMT2AMEN1TDP1LMNA | |
| SCHEMBL29952977 | 0.73 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1ALDH3A1ALDH1A3 | |
| SCHEMBL29954704 | 0.73 | KMT2A (0.42) | ALDH1A1KMT2AMEN1TDP1LMNA | |
| SCHEMBL29951806 | 0.72 | KMT2A (0.41) | ALDH1A1KMT2AMEN1TDP1LMNA | |
| SCHEMBL29954725 | 0.71 | ICMT (0.35) | ALDH1A1ALDH3A1ALDH1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |