Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | MMP9 | P14780 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953599 | 0.84 | MTNR1A (0.49) | MAOAMAOBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL29955292 | 0.76 | ENPP2 (0.55) | MTNR1AMTNR1BENPP2RAB9ASMN1; SMN2 | |
| SCHEMBL15332971 | 0.76 | LIPG (0.46) | APPMAOAMAOBENPP2NPC1 | |
| SCHEMBL2553795 | 0.75 | LIPG (0.39) | ALDH1A1SMN1; SMN2POLBDAOMAPT | |
| SCHEMBL15331471 | 0.74 | CXCR2 (0.40) | ALDH1A1SMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL29955348 | 0.73 | APP (0.64) | APPMAOAMAOBMTNR1AMTNR1B | |
| SCHEMBL2433694 | 0.73 | APP (0.69) | APPMAOAMAOBALDH1A1NPC1 | |
| SCHEMBL29957934 | 0.73 | ENPP2 (0.54) | APPMAOAMAOBMTNR1AMTNR1B | |
| SCHEMBL29953070 | 0.71 | SLC6A2 (0.43) | MAOAMAOBALDH1A1ENPP2KMT2A | |
| SCHEMBL3228582 | 0.70 | APP (0.82) | APPMAOAMAOBALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |