Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2553614 | 0.83 | DHFR (0.39) | SLC6A2SLC6A4SLC6A3ENPP2TDP1 | |
| SCHEMBL29953599 | 0.79 | MTNR1A (0.49) | ENPP2DHFRALDH1A1LMNAMAOA | |
| SCHEMBL15331471 | 0.79 | CXCR2 (0.40) | L3MBTL1MEN1ALDH1A1KMT2ACXCR2 | |
| SCHEMBL2553795 | 0.77 | LIPG (0.39) | MAPTL3MBTL1ALDH1A1LMNACXCR2 | |
| SCHEMBL28104581 | 0.76 | QRFPR (0.45) | SLC6A2SLC6A4SLC6A3TDP1MAPT | |
| SCHEMBL2562700 | 0.75 | DAO (0.40) | ENPP2TDP1MAPTGAAALPG | |
| SCHEMBL15331023 | 0.74 | TDP1 (0.37) | SLC6A2SLC6A4SLC6A3ENPP2TDP1 | |
| Methyl Alcohol SCHEMBL27517044 | 0.74 | TDP1 (0.50) | SLC6A4TDP1MAPTGAAALPG | |
| SCHEMBL29954163 | 0.74 | LPL (0.42) | ENPP2TDP1MAPTGAAALPG | |
| SCHEMBL29956268 | 0.73 | ENPP2 (0.49) | ENPP2TDP1MAPTGAAALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |