Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952267 | 1.00 | ACE (0.40) | ACELTA4HTACR1HSD17B10HRH3 | |
| SCHEMBL6962733 | 0.81 | ALDH1A1 (0.37) | ACEHSD17B10POLBL3MBTL1 | |
| SCHEMBL23959763 | 0.81 | TSHR (0.37) | TACR1POLBL3MBTL1OGFRL1 | |
| SCHEMBL500406 | 0.77 | ALDH1A1 (0.48) | HSD17B10HRH3POLBL3MBTL1SLC6A9 | |
| SCHEMBL472180 | 0.77 | ACE (0.45) | ACELTA4HHSD17B10REN | |
| SCHEMBL25202526 | 0.77 | ALDH1A1 (0.48) | HSD17B10HRH3POLBL3MBTL1SLC6A9 | |
| SCHEMBL472181 | 0.77 | ACE (0.45) | ACELTA4HHSD17B10REN | |
| SCHEMBL24307669 | 0.75 | TSHR (0.39) | TACR1POLBL3MBTL1 | |
| SCHEMBL7763371 | 0.75 | POLB (0.52) | ACELTA4HHRH3POLBL3MBTL1 | |
| SCHEMBL7882058 | 0.75 | ACE (0.38) | ACELTA4HTACR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |