Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956516 | 0.86 | HRH3 (0.35) | ALDH1A1LMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL29953763 | 0.83 | ENPP2 (0.42) | ALDH1A1LMNAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL4469053 | 0.77 | L3MBTL1 (0.55) | ALDH1A1LMNAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL29951540 | 0.76 | HPGD (0.49) | NFE2L2HIF1ACA1CA2ENPP2 | |
| SCHEMBL3289627 | 0.73 | PARP10 (0.58) | — | |
| SCHEMBL14167586 | 0.73 | CA2 (0.48) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL20830808 | 0.71 | NFE2L2 (0.51) | NFE2L2CA1CA2ENPP2HRH3 | |
| SCHEMBL29955567 | 0.71 | KMT2A (0.57) | CA1CA2ENPP2TSHRKMT2A | |
| SCHEMBL2561635 | 0.71 | HPGD (0.44) | CA1CA2ENPP2 | |
| SCHEMBL2617897 | 0.71 | KCNA3 (0.52) | ALDH1A1LMNAMAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |