Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 5/20 | 0.35 |
| ▸ | NOS2 | P35228 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184838 | 1.00 | NOS3 (0.35) | NOS3NOS2KMT2AKDM4EMEN1 | |
| SCHEMBL8131114 | 0.80 | NOS2 (0.37) | NOS3NOS2KMT2AMEN1NOS1 | |
| SCHEMBL30937638 | 0.78 | ALDH1A1 (0.38) | KMT2AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL529516 | 0.78 | ALDH1A1 (0.38) | KMT2AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL305898 | 0.77 | CCR1 (0.39) | NOS3NOS2KMT2AKDM4EMEN1 | |
| SCHEMBL31146149 | 0.77 | NR4A2 (0.32) | KMT2AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL16333419 | 0.76 | AURKA (0.40) | NOS3NOS2KMT2AMEN1NOS1 | |
| SCHEMBL16649178 | 0.76 | RAB9A (0.33) | KDM4EALDH1A1CYP2A6HTT | |
| SCHEMBL29953139 | 0.76 | ERN1 (0.35) | KMT2AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL29956118 | 0.74 | ALDH1A1 (0.48) | KMT2AKDM4EMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |