Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957067 | 0.82 | SIRT1 (0.45) | LMNAHPGDMAPTSIRT1ALDH1A1 | |
| SCHEMBL29956270 | 0.78 | KDM4E (0.44) | GSK3BCDK5CHUK | |
| SCHEMBL15332502 | 0.78 | KDM4E (0.42) | MAPTALDH1A1HTT | |
| SCHEMBL15330972 | 0.78 | KIF11 (0.44) | MAPT | |
| SCHEMBL3223692 | 0.78 | ALDH1A1 (0.50) | HPGDMAPTSIRT1ALDH1A1HSD17B10 | |
| SCHEMBL29957756 | 0.78 | ALDH1A1 (0.50) | HPGDMAPTSIRT1ALDH1A1HSD17B10 | |
| SCHEMBL7254612 | 0.78 | AHR (0.43) | HPGDMAPTGSK3BSIRT1ALDH1A1 | |
| SCHEMBL29952591 | 0.77 | MAPT (0.52) | LMNAMAPTALDH1A1HTT | |
| SCHEMBL29957489 | 0.75 | SIRT1 (0.46) | LMNAHPGDMAPTSIRT1ALDH1A1 | |
| SCHEMBL29953259 | 0.75 | KDM4E (0.48) | HPGDMAPTALDH1A1HSD17B10MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |