Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957489 | 0.93 | SIRT1 (0.46) | SIRT1RECQLSIRT2ALDH1A1KDM4E | |
| SCHEMBL29957448 | 0.82 | CYP2D6 (0.42) | SIRT1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL3223692 | 0.81 | ALDH1A1 (0.50) | SIRT1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL29957756 | 0.81 | ALDH1A1 (0.50) | SIRT1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL15330972 | 0.81 | KIF11 (0.44) | MAPTALOX15MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15332502 | 0.81 | KDM4E (0.42) | ALDH1A1KDM4EMAPTGAAALOX15 | |
| SCHEMBL29956270 | 0.78 | KDM4E (0.44) | KDM4EMEN1KMT2A | |
| SCHEMBL29953259 | 0.78 | KDM4E (0.48) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL7254612 | 0.78 | AHR (0.43) | SIRT1SIRT2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL1428978 | 0.77 | MTNR1A (0.52) | SIRT1ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |