Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NQO1 | P15559 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 6/20 | 0.42 |
| ▸ | GABRD | O14764 | 6/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 6/20 | 0.42 |
| ▸ | GABRE | P78334 | 6/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 6/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845026 | 1.00 | MEN1 (0.56) | MEN1LMNAKMT2ANQO1PTPN1 | |
| SCHEMBL29952602 | 0.84 | NQO1 (0.49) | NQO1PTPN1CDC25ACDC25CCA2 | |
| SCHEMBL28091488 | 0.82 | NQO1 (0.53) | MEN1LMNAKMT2ANQO1PTPN1 | |
| SCHEMBL3196866 | 0.81 | CA2 (0.57) | MEN1LMNAKMT2ANQO1CA2 | |
| SCHEMBL9910631 | 0.81 | CA9 (0.48) | PTPN1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29955895 | 0.81 | CA9 (0.48) | PTPN1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29951008 | 0.81 | NQO1 (0.61) | MEN1LMNAKMT2ANQO1PTPN1 | |
| SCHEMBL5273182 | 0.77 | CA9 (0.53) | MEN1LMNAKMT2ANQO1CA2 | |
| SCHEMBL10604237 | 0.74 | HSD17B3 (0.54) | LMNAKMT2ANQO1GABRPGABRD | |
| SCHEMBL28455437 | 0.73 | HSD17B3 (0.60) | MEN1LMNAKMT2ANQO1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |