SCHEMBL29955895

SCHEMBL29955895

O=Cc1c(Cl)c2cc(Br)ccc2oc1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 7/20 0.48
CA12 O43570 5/20 0.48
PTPN1 P18031 1/20 0.44
PIM1 P11309 3/20 0.44
GABRP O00591 4/20 0.42
GABRD O14764 4/20 0.42
GABRA1 P14867 4/20 0.42
GABRB1 P18505 4/20 0.42
GABRG2 P18507 4/20 0.42
GABRB3 P28472 4/20 0.42
GABRA5 P31644 4/20 0.42
GABRA3 P34903 4/20 0.42
GABRA2 P47869 4/20 0.42
GABRB2 P47870 4/20 0.42
GABRA4 P48169 4/20 0.42
GABRE P78334 4/20 0.42
GABRA6 Q16445 4/20 0.42
GABRG1 Q8N1C3 4/20 0.42
GABRG3 Q99928 4/20 0.42
GABRQ Q9UN88 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9910631 1.00 CA9 (0.48) CA9CA12PTPN1PIM1GABRP
SCHEMBL29952602 0.84 NQO1 (0.49) CA9CA12PTPN1CA2CA1
SCHEMBL29957740 0.81 MEN1 (0.56) CA9CA12PTPN1GABRPGABRD
SCHEMBL17845026 0.81 MEN1 (0.56) CA9CA12PTPN1GABRPGABRD
SCHEMBL3196866 0.81 CA2 (0.57) CA9CA12CA2CA1CSNK2A2
SCHEMBL29953189 0.81 CA12 (0.62) CA9CA12PTPN1PIM1GABRP
SCHEMBL29954634 0.79 CYP2A6 (0.45) CA9CA12PTPN1PIM1GABRP
SCHEMBL16974052 0.79 CYP2A6 (0.45) CA9CA12PTPN1PIM1GABRP
SCHEMBL5273182 0.77 CA9 (0.53) CA9CA12CA2MAOA
SCHEMBL28455437 0.73 HSD17B3 (0.60) CA9CA12CSNK2A2CSNK2BCSNK2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed