Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 6/20 | 0.42 |
| ▸ | DDIT3 | P35638 | 1/20 | 0.41 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 3/20 | 0.38 |
| ▸ | MMP13 | P45452 | 3/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | LOX | P28300 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2414928 | 0.91 | ENPP2 (0.53) | ENPP2DDIT3MMP13HTR2AMAPT | |
| SCHEMBL29952232 | 0.83 | ENPP2 (0.46) | ENPP2NAMPTHTR2AHTR2CKCNH2 | |
| SCHEMBL29951042 | 0.81 | DRD2 (0.44) | ENPP2 | |
| SCHEMBL16093162 | 0.81 | APLNR (0.44) | ENPP2MMP8MMP13MMP1 | |
| SCHEMBL31518328 | 0.79 | NAMPT (0.45) | NAMPTDDIT3PIK3C3MMP8MMP13 | |
| SCHEMBL9576066 | 0.79 | ESR1 (0.47) | ENPP2NAMPTDDIT3PIK3C3MMP8 | |
| SCHEMBL31518353 | 0.79 | LMNA (0.45) | NAMPTDDIT3PIK3C3MMP8MMP13 | |
| SCHEMBL776895 | 0.79 | MAPT (0.55) | MMP8MMP13MMP1HTR2AMAPT | |
| SCHEMBL2924761 | 0.77 | LMNA (0.46) | ENPP2NAMPTDDIT3PIK3C3MMP8 | |
| SCHEMBL777971 | 0.77 | MAPT (0.56) | MMP8MMP13MMP1HTR2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |