Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 6/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956270 | 0.93 | KDM4E (0.44) | KDM4EKIF11CNR1MEN1KMT2A | |
| SCHEMBL15332675 | 0.87 | KIF11 (0.41) | KIF11MEN1KMT2ATRPV1 | |
| SCHEMBL29953069 | 0.86 | KIF11 (0.42) | KIF11MEN1KMT2ATRPV1S1PR1 | |
| SCHEMBL29957489 | 0.80 | SIRT1 (0.46) | KDM4EMEN1KMT2A | |
| SCHEMBL15330972 | 0.80 | KIF11 (0.44) | KIF11MEN1KMT2ATRPV1S1PR1 | |
| SCHEMBL15331776 | 0.77 | KDM4E (0.42) | KDM4EKIF11CNR1MEN1KMT2A | |
| SCHEMBL29951013 | 0.77 | MTNR1A (0.55) | KDM4EMEN1KMT2A | |
| SCHEMBL1429356 | 0.77 | MTNR1A (0.55) | KDM4EMEN1KMT2A | |
| SCHEMBL29952812 | 0.76 | MAPT (0.52) | CNR1MEN1KMT2A | |
| SCHEMBL1428728 | 0.75 | MTNR1A (0.54) | KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |