Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.42 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
| ▸ | HTR1B | P28222 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15332675 | 0.99 | KIF11 (0.41) | KIF11HTR1DHTR1BTRPV1GHSR | |
| SCHEMBL15330972 | 0.95 | KIF11 (0.44) | KIF11HTR1DHTR1BTRPV1GHSR | |
| SCHEMBL29952771 | 0.86 | KDM4E (0.42) | KIF11TRPV1MEN1KMT2AS1PR1 | |
| SCHEMBL29956270 | 0.81 | KDM4E (0.44) | KIF11TRPV1MEN1KMT2A | |
| SCHEMBL29957489 | 0.81 | SIRT1 (0.46) | MEN1MAPTALOX15KMT2ASMN1; SMN2 | |
| SCHEMBL10067373 | 0.81 | KIF11 (0.46) | KIF11HTR1DHTR1BTRPV1GHSR | |
| SCHEMBL1428728 | 0.79 | MTNR1A (0.54) | MEN1MAPTKMT2AMTNR1AMTNR1B | |
| SCHEMBL15331776 | 0.78 | KDM4E (0.42) | KIF11HTR1DHTR1BMEN1GLA | |
| SCHEMBL29951013 | 0.78 | MTNR1A (0.55) | MEN1MAPTKMT2AMTNR1AMTNR1B | |
| SCHEMBL1429356 | 0.78 | MTNR1A (0.55) | MEN1MAPTKMT2AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |