SCHEMBL29953000

SCHEMBL29953000

CCOc1ncc(C=O)cc1C

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.41
GAA P10253 1/20 0.41
LMNA P02545 1/20 0.36
SRC P12931 1/20 0.36
KDM4E B2RXH2 2/20 0.36
L3MBTL1 Q9Y468 3/20 0.35
DHFR P00374 1/20 0.35
PTGER4 P35408 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
PKM P14618 1/20 0.35
TACR2 P21452 1/20 0.34
SLC13A5 Q86YT5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28923138 0.84 SRC (0.35) ALDH1A1SRCKDM4EPTGER4MAPT
SCHEMBL15719149 0.83 FDPS (0.40) ALDH1A1GAASRCKDM4EMAPT
SCHEMBL22666896 0.80 ALDH1A1 (0.40) ALDH1A1GAALMNAKDM4EL3MBTL1
SCHEMBL16762140 0.80 PTGS2 (0.39) ALDH1A1SRCKDM4EL3MBTL1MAPT
SCHEMBL4540418 0.77 DRD1 (0.38) ALDH1A1GAASRCKDM4EL3MBTL1
SCHEMBL31623890 0.77 MAOA (0.51) ALDH1A1LMNAL3MBTL1MAPTHPGD
SCHEMBL16388761 0.76 NOS3 (0.45) PKMSLC13A5
SCHEMBL16838826 0.76 SCN9A (0.38) HPGD
SCHEMBL2703051 0.75 ALDH1A1 (0.50) ALDH1A1GAALMNAKDM4EL3MBTL1
SCHEMBL21078798 0.75 SSTR4 (0.33) ALDH1A1KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed