Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TDP2 | O95551 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4516641 | 0.82 | TSHR (0.64) | TSHRLMNAPGRALDH1A1ALOX15 | |
| SCHEMBL7838339 | 0.82 | LMNA (0.64) | TSHRLMNAPGRALDH1A1TDP2 | |
| SCHEMBL28962659 | 0.82 | CA1 (0.50) | TSHRLMNACA1CA2MGLL | |
| SCHEMBL6738366 | 0.82 | TSHR (0.76) | TSHRLMNAPGRALDH1A1ALOX15 | |
| SCHEMBL4667734 | 0.81 | ALDH1A1 (0.63) | TSHRLMNAPGRALDH1A1ALOX15 | |
| SCHEMBL127723 | 0.80 | TSHR (0.61) | TSHRLMNACA1CA2ALDH1A1 | |
| SCHEMBL29758194 | 0.80 | TSHR (0.61) | TSHRLMNACA1CA2ALDH1A1 | |
| SCHEMBL29526232 | 0.80 | TSHR (0.67) | TSHRLMNAPGRALDH1A1ALOX15 | |
| SCHEMBL2009026 | 0.80 | TSHR (0.67) | TSHRLMNAPGRALDH1A1ALOX15 | |
| SCHEMBL11392466 | 0.80 | TSHR (0.73) | TSHRLMNAPGRALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |