Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3908300 | 1.00 | HDAC3 (0.54) | HDAC3HDAC1HDAC2HSD11B1MGLL | |
| SCHEMBL3920568 | 1.00 | HDAC3 (0.54) | HDAC3HDAC1HDAC2HSD11B1MGLL | |
| SCHEMBL1341836 | 0.98 | HDAC3 (0.51) | HDAC3HDAC1HDAC2HSD11B1MGLL | |
| SCHEMBL29990240 | 0.98 | HDAC3 (0.51) | HDAC3HDAC1HDAC2HSD11B1MGLL | |
| SCHEMBL8880100 | 0.94 | HSD11B1 (0.48) | HDAC3HDAC1HDAC2HSD11B1MGLL | |
| SCHEMBL6575271 | 0.90 | HSD11B1 (0.50) | HDAC3HDAC1HDAC2HSD11B1MGLL | |
| SCHEMBL3918618 | 0.82 | ALDH1A1 (0.47) | HDAC3HDAC1HDAC2HSD11B1MGLL | |
| SCHEMBL5209254 | 0.82 | HTR3E (0.55) | HSD11B1MGLLALDH1A1KDM4EGAA | |
| Hydrochloric Acid SCHEMBL5212698 | 0.81 | HTR3E (0.54) | HSD11B1MGLLALDH1A1KDM4EGAA | |
| SCHEMBL26085824 | 0.80 | KDM4E (0.49) | HDAC3HDAC1HDAC2HSD11B1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |