Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955363 | 0.83 | HCAR1 (0.40) | HCAR1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL15331814 | 0.81 | KCNN4 (0.46) | HCAR1ALDH1A1KMT2AMEN1ERN1 | |
| SCHEMBL15332328 | 0.80 | MGLL (0.37) | HCAR1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL15331152 | 0.78 | PKM (0.44) | HCAR1ALDH1A1MAPTLMNAHTT | |
| SCHEMBL2559232 | 0.74 | ERN1 (0.42) | HCAR1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL29951698 | 0.74 | ALDH1A1 (0.37) | HCAR1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL29951366 | 0.74 | HIF1A (0.45) | MAPTKMT2AMEN1LMNACYP2C9 | |
| SCHEMBL29954784 | 0.72 | NPC1 (0.48) | MAPTKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL10850556 | 0.72 | EPHB3 (0.43) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL9217131 | 0.70 | GAA (0.54) | ALDH1A1MAPTKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |