Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | CTH | P32929 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290645 | 1.00 | KDM4E (0.38) | KDM4EMPIL3MBTL1NAPRTMAPT | |
| SCHEMBL29354585 | 0.82 | KDM4E (0.49) | KDM4EMPIL3MBTL1NPC1 | |
| SCHEMBL29091457 | 0.74 | ALDH1A1 (0.45) | KDM4EMPIL3MBTL1MAPTHTT | |
| SCHEMBL29232877 | 0.74 | ENPP2 (0.37) | KDM4EL3MBTL1MAPTHTTNPC1 | |
| SCHEMBL29953696 | 0.74 | ALDH1A1 (0.45) | KDM4EMPIL3MBTL1MAPTHTT | |
| SCHEMBL729391 | 0.73 | HSP90AA1 (0.38) | KDM4ENAPRTMAPTHTT | |
| SCHEMBL982637 | 0.73 | LMNA (0.38) | KDM4EL3MBTL1MAPTHTTNFE2L2 | |
| SCHEMBL3563575 | 0.73 | TRIM24 (0.38) | KDM4EMAPTHTTNPC1 | |
| SCHEMBL2108200 | 0.73 | NOS3 (0.46) | KDM4EL3MBTL1MAPTHTTNPC1 | |
| SCHEMBL29517081 | 0.73 | HSP90AA1 (0.38) | KDM4ENAPRTMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |