Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.45 |
| ▸ | METAP2 | P50579 | 2/20 | 0.45 |
| ▸ | METAP1 | P53582 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | COMT | P21964 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29091457 | 1.00 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1METAP2METAP1MMP2 | |
| SCHEMBL29232877 | 0.76 | ENPP2 (0.37) | L3MBTL1MMP2TSHRKDM4EHSP90AA1 | |
| SCHEMBL29517081 | 0.74 | HSP90AA1 (0.38) | ALDH1A1HDAC8KDM4EHSP90AA1KMT2A | |
| SCHEMBL290645 | 0.74 | KDM4E (0.38) | L3MBTL1KDM4ENPC1HTTMAPT | |
| SCHEMBL29953457 | 0.74 | KDM4E (0.38) | L3MBTL1KDM4ENPC1HTTMAPT | |
| SCHEMBL2108200 | 0.74 | NOS3 (0.46) | L3MBTL1METAP2KDM4EHSP90AA1NPC1 | |
| SCHEMBL982637 | 0.74 | LMNA (0.38) | ALDH1A1L3MBTL1METAP2METAP1TSHR | |
| SCHEMBL729391 | 0.74 | HSP90AA1 (0.38) | ALDH1A1HDAC8KDM4EHSP90AA1KMT2A | |
| SCHEMBL3563575 | 0.74 | TRIM24 (0.38) | ALDH1A1MMP2TSHRKDM4EHSP90AA1 | |
| SCHEMBL28983747 | 0.71 | TRIM24 (0.53) | ALDH1A1L3MBTL1TSHRKDM4EHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |